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3Medicinal

White willow bark

Also sold as Salicin

Aspirin-like action — the same bleeding and stomach cautions apply.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

55/100Moderate
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: low back pain, unsurprisingly given it is aspirin-adjacent.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Short courses for pain flares.

Who it's actually for

Adults with musculoskeletal pain who tolerate aspirin.

Safe upper limit

Unverified
Treat as you would aspirin; 120–240 mg salicin daily in trials
It is chemically close to aspirin. Bleeding risk, stomach irritation, and Reye's syndrome risk in children are all real.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Do not give to children or teenagers.
  • Avoid entirely if you are on an anticoagulant or have aspirin allergy.