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3Medicinal

Valerian root

Also sold as Valeriana officinalis

Traditional sedative herb; sedates additively with alcohol and sleep drugs.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

38/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: sleep quality — trials are small and results inconsistent.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Short courses of two to six weeks.

Who it's actually for

Mild sleep difficulty, as a short-term aid.

Safe upper limit

Unverified
No formal limit; 300–600 mg extract before bed
Additive sedation is the main risk. Rare liver reactions reported.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Do not combine with alcohol, benzodiazepines, or sleep medication.
  • Don't drive if it leaves you groggy in the morning.