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3Medicinal

Rhodiola rosea

Also sold as Golden root, arctic root

Studied for fatigue and burnout; usually taken in the morning.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

45/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: fatigue in small trials of variable quality.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Short courses of four to twelve weeks.

Who it's actually for

People with stress-related fatigue rather than a medical cause of tiredness.

Safe upper limit

Unverified
No formal limit; 200–600 mg extract daily in trials
Can be activating enough to disrupt sleep or trigger agitation.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Take before noon.
  • Can trigger mania in bipolar disorder — avoid without psychiatric advice.