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3Medicinal

Red yeast rice

Also sold as Monacolin K, RYR

Chemically a low-dose statin. The same monitoring applies.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

85/100Very strong
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: lowering LDL — because it contains a statin.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Ongoing only with lipid and liver monitoring, exactly as with a prescribed statin.

Who it's actually for

People managing cholesterol who should be having this conversation with a doctor.

Safe upper limit

Unverified
Monacolin K content is capped at 3 mg per day in the EU
It is a statin by another name — muscle damage, liver stress, and every statin interaction apply. Product potency also varies wildly between brands.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Never combine with a prescription statin.
  • Get liver enzymes checked.
  • Contamination with citrinin, a kidney toxin, has been found in unregulated products.