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3Medicinal

Lemon balm

Also sold as Melissa officinalis

Gentle traditional calmative, often combined with valerian.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

35/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: mild anxiety and sleep quality in small trials.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Short courses.

Who it's actually for

Mild situational anxiety or difficulty settling.

Safe upper limit

Unverified
No formal limit; 300–600 mg extract
Mild sedation, additive with other sedatives. May affect thyroid function at high doses.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Commonly paired with valerian in sleep formulas.
  • Avoid with thyroid medication without discussing it first.