Effective for anxiety but carries documented liver-injury risk.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
65/100Moderate
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: anxiety — effective, which is why the liver risk matters.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Short courses at most, and not if you drink regularly.
Who it's actually for
Anxiety, with genuine caution and ideally medical oversight.
Safe upper limit
Unverified
Restricted or banned in several countries; 250 mg kavalactones daily is a common cap
Documented cases of severe liver failure, some requiring transplant. Risk rises with alcohol and other liver-processed drugs.