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4Optional

Hyaluronic acid

Also sold as HA, sodium hyaluronate

Oral form for skin hydration; evidence is modest.

TrustedSupp Tier System™ · Tier 4Take by choice, or not at all

Evidence strength

40/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: skin hydration in small, often industry-funded trials.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Eight to twelve weeks to judge skin effects.

Who it's actually for

People interested in skin hydration, with realistic expectations.

Safe upper limit

Unverified
No formal limit; 120–240 mg daily in trials
Well tolerated.
No source or citation attached yet.

Interactions to know about

No commonly documented medication clashes in our data. That is not the same as none existing.

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Injected and topical HA work by entirely different mechanisms — oral results are far more modest.