A cholinesterase inhibitor — pharmacologically active, not benign.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
45/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: cognition in dementia trials of variable quality.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Short courses only, with medical oversight.
Who it's actually for
Not a casual nootropic. Discuss with a doctor.
Safe upper limit
Unverified
No formal limit; 50–200 mcg daily. Treat as a drug
Genuinely drug-like. Can cause slow heart rate, nausea, and cholinergic side effects, and stacks dangerously with dementia medication.