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4Optional

HMB

Also sold as Beta-hydroxy beta-methylbutyrate

Muscle preservation, mainly relevant in untrained or older populations.

TrustedSupp Tier System™ · Tier 4Take by choice, or not at all

Evidence strength

45/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: preserving lean mass during bed rest, ageing, or calorie restriction.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Ongoing during periods of muscle loss risk.

Who it's actually for

Older adults, people on bed rest, or in a significant calorie deficit. Trained lifters see little.

Safe upper limit

Unverified
No formal limit; 3 g daily in trials
Well tolerated across studies.
No source or citation attached yet.

Interactions to know about

No commonly documented medication clashes in our data. That is not the same as none existing.

Run your full list through the interaction check.

Practical notes

  • Benefits shrink the more trained you are.
  • Creatine is a better first choice for almost everyone.