Also sold as Reduced glutathione, liposomal glutathione, S-acetyl glutathione
The body's main antioxidant, sold for detox and skin lightening — oral supplements have limited evidence of raising tissue levels.
TrustedSupp Tier System™ · Tier 4Take by choice, or not at all
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
20/100Weak
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: raising blood glutathione in some trials; clinical benefit claims are unsupported.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Not established.
Who it's actually for
Limited justification; NAC is a better-studied way to support the body's own glutathione production.
Safe upper limit
Unverified
No formal upper limit; 250–1,000 mg daily in oral trials
Oral glutathione appears safe at studied doses. Injectable glutathione used for skin lightening has been associated with serious adverse events and is not approved for that purpose in many countries.