Long-used for knee osteoarthritis; benefit is modest and debated.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
38/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: knee osteoarthritis — the largest trials found little over placebo.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Three to six month trial. If nothing changes, stop.
Who it's actually for
Knee osteoarthritis, with modest expectations.
Safe upper limit
Unverified
No formal limit; 1,500 mg daily is standard
Can mildly raise blood sugar and has been linked to increased INR on warfarin.