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3Medicinal

Evening primrose oil

Also sold as EPO, GLA, gamma-linolenic acid

Used for breast tenderness and eczema with mixed results.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

32/100Weak
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: cyclical breast pain; eczema claims have not held up in reviews.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Three months to judge effect.

Who it's actually for

Cyclical breast tenderness, with modest expectations.

Safe upper limit

Unverified
No formal limit; 1–3 g daily is typical
Mild antiplatelet effect. May lower seizure threshold.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Systematic reviews have not supported the eczema claims.
  • Avoid with epilepsy and stop before surgery.