← Back
3Medicinal

DHM (Dihydromyricetin)

Also sold as Hovenia dulcis, japanese raisin tree, hangover supplement

Marketed for hangovers and alcohol metabolism. Popular, but the human evidence is thin.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

25/100Weak
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: hangover symptoms — largely extrapolated from animal studies.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Occasional, situational use. There is no basis for taking it daily.

Who it's actually for

People looking to reduce hangover symptoms — with the caveat that the evidence is mostly animal studies.

Safe upper limit

Unverified
No formal limit; 300–600 mg is typical. Human safety data is limited
Short-term use appears well tolerated, but there is no long-term safety data and no established limit.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Most of the supporting research is in rodents; human trials are few and small.
  • It does not reduce blood alcohol or make drinking safer — treating it as protection is the real risk here.
  • Interacts with anything else processed by the liver, including alcohol itself.