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3Medicinal

CLA

Also sold as Conjugated linoleic acid

A fatty acid sold for fat loss — effects are tiny, and some studies found it worsened insulin sensitivity.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

15/100Weak
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: very small fat-loss effects in trials, with some metabolic downsides.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Not recommended for long-term use.

Who it's actually for

Limited justification.

Safe upper limit

Unverified
No formal upper limit; 3–6 g daily in trials
Digestive upset is common. Some trials found worsened insulin resistance and lower HDL cholesterol, particularly with the trans-10, cis-12 form.
No source or citation attached yet.

Interactions to know about

Run your full list through the interaction check.

Practical notes

  • Average fat loss in trials is very small.
  • People with diabetes or pre-diabetes should avoid it.
  • May have mild blood-thinning effects.