Usually paired with glucosamine; similarly mixed evidence.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
35/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: knee osteoarthritis — evidence is weak and inconsistent.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Three to six month trial alongside glucosamine. If nothing changes, stop.
Who it's actually for
Knee osteoarthritis, with modest expectations.
Safe upper limit
Unverified
No formal limit; 800–1,200 mg daily is standard
Well tolerated. The main caution is a possible effect on blood clotting.