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1Essential

Choline

Also sold as Citicoline, choline bitartrate, alpha-GPC

Most diets fall short; the gap is structural rather than episodic.

TrustedSupp Tier System™ · Tier 1Take persistently

Evidence strength

68/100Moderate
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: meeting a genuine dietary shortfall, particularly in pregnancy.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Ongoing if you eat few eggs and little liver. Demand rises notably in pregnancy.

Who it's actually for

Pregnant women, plant-based eaters, and people who avoid eggs.

Safe upper limit

Unverified
3,500 mg per day
Excess causes a fishy body odour, low blood pressure, and sweating.
No source or citation attached yet.

Interactions to know about

No commonly documented medication clashes in our data. That is not the same as none existing.

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Two eggs cover a large share of daily needs.
  • Most prenatal vitamins contain far less choline than pregnancy requires.