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3Medicinal

Chasteberry

Also sold as Vitex agnus-castus

PMS and cycle irregularity; affects prolactin and hormonal contraception.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

58/100Moderate
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: PMS symptoms and cycle regularity.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Three cycles to judge effect.

Who it's actually for

Women with PMS or luteal phase concerns, not on hormonal contraception.

Safe upper limit

Unverified
No formal limit; 20–40 mg extract daily
Acts on the pituitary and prolactin. Not benign hormonally.
No source or citation attached yet.

Interactions to know about

Run your full list through the interaction check.

Practical notes

  • Can interfere with hormonal contraception and fertility treatment.
  • Avoid in pregnancy.