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3Medicinal

Black seed oil

Also sold as Nigella sativa, black cumin, kalonji

A traditional remedy with meta-analyses showing modest drops in blood sugar, cholesterol, and blood pressure.

TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

Evidence strength

45/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: modest reductions in blood sugar, lipids, and blood pressure in meta-analyses of small trials.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Course-based, typically 8–12 weeks with monitoring.

Who it's actually for

People working on metabolic markers, especially if already monitoring blood sugar or blood pressure.

Safe upper limit

Unverified
No formal upper limit; 1–3 g of oil daily in most trials
Generally well tolerated at studied doses. It adds to the effect of diabetes, blood pressure, and anticoagulant medication. Rare case reports of kidney injury exist at high doses.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Effects are modest — a complement to, not a replacement for, treatment.
  • Monitor blood sugar if you take diabetes medication.
  • Topical use has caused allergic skin reactions.