Used in courses for stress, cortisol, and sleep quality.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
58/100Moderate
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: short-term stress and anxiety scores; long-term data is limited.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Eight to twelve week courses with breaks, rather than continuous use.
Who it's actually for
People with sustained stress or poor sleep — not a general daily supplement.
Safe upper limit
Unverified
No formal limit; trials typically use 300–600 mg of extract daily
Rare but documented cases of liver injury, some serious. It also nudges thyroid hormones upward. Herbal, not a nutrient — no IOM/EFSA UL framework applies. The liver-injury case reports are the load-bearing safety fact and need their own citation search.