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3Medicinal

Apigenin

Also sold as Chamomile flavonoid

The flavonoid in chamomile, popularised as a sleep aid — isolated apigenin has very little human sleep research.

TrustedSupp Tier System™ · Tier 3Take as a defined course

Evidence strength

15/100Weak
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: sleep quality via chamomile extract studies; isolated apigenin is barely studied.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Short-term, situational use.

Who it's actually for

People wanting a gentle sleep aid; chamomile tea is the traditional and cheaper route.

Safe upper limit

Unverified
No formal upper limit; the commonly promoted 50 mg dose lacks strong trial backing
Well tolerated in the limited data. It has mild sedative effects that can add to other sedatives.
No source or citation attached yet.

Interactions to know about

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Most evidence is for chamomile extract, not isolated apigenin.
  • May add to the effect of sleep medication and alcohol.
  • Avoid with ragweed or daisy-family allergy.