Serotonin precursor — do not combine with antidepressants.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
40/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: mood; trials are small and the safety profile constrains use.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Short courses only, and not alongside psychiatric medication.
Who it's actually for
Discuss with a doctor first if you have any mood diagnosis.
Safe upper limit
Unverified
No formal limit; 50–300 mg daily in trials
Serotonin syndrome risk when stacked with serotonergic drugs. This can be fatal.